Students will build on their foundation of genetics by investigating current techniques used in genomic research and genetic engineering. Concepts such as PCR, DNA fingerprinting, transformation, and cloning and their use in therapeutic and forensic science will be examined. To further explore this continually growing branch of science learners will participate in online/interactive simulations as well perform gel electrophoresis and bacterial transformation. Gel electrophoresis will be used to model the use of biotechnology in forensics. Students will run samples of DNA to observe genomic differences in amounts of introns, illustrating how individuals have unique DNA fingerprints. Transgenics, the incorporation of foreign DNA, will be used to explore the potential of these tools by transforming bacteria to express pGLO, a bioluminescence gene from jellyfish. These laboratory activities will be use Student mastery of genetic technology will culminate in a debate addressing the ethics behind the exploration and use of genetic manipulation in therapeutic/ecological roles.
Lectures and Notes:
Honors Biology Syllabus
Unit 7 PowerPoint Lecture
Unit 7 Student Notes
Unit 7 Study Guide
Unit 7 Study Guide (student created)
Quizlet #2: Unit 7 Review (student Created)
Quizlet: Unit 7 Review (student created)
Labs and Classroom Activities:
Lab: Online Karyotyping Activity (site1) (site 2) (key)
Lab: pedigree analysis (key)
Lab: Epigenetics (simulation) (key)
Lab: DNA Fingerprinting (key)
Lab: UV Light and Skin Cancer (rubric)
Lab: Cloning (key)
Lab: Wheat Germ DNA Extraction
Lab: Virtual Gel Electrophoresis
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Epigenetics: Why Inheritance Is Weirder Than We Thought
TedEd What is epigenetics?
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Learn.Genetics: Insights From Identical Twins